Very persistent toothache is always a sign that you need to see a dentist as soon as practicable. In the meantime, you should try to obtain relief by rinsing the mouth with water and trying to clean out debris from any obvious cavities. Use dental floss to remove any food that might be trapped within the cavity (especially between the teeth).Take pain relief if necessary, using pain medicines that you know you are safe with. Remember, no pain relief tablets will work directly on the tooth. They must be swallowed as directed. If placed on the tooth, they can cause more trouble (especially aspirin).